对子SAMD9的结构和功能研究揭示了一个独特的tRNase模块,它是抗病毒活动的基础

概括

无菌阿尔法基因域含有9 (SAMD9) 和SAMD9类 (SAMD9L) 蛋白质对于抗病毒防御至关重要. 子SAMD9 (rSAMD9) 尽管具有独特的结构变异,但仍然保留了tRNA分裂和抗病毒功能,证明了进化灵活性.

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