舌头体积和脂肪含量对阻塞性睡眠呼吸暂停的影响:元分析和系统审查
Emily Baker1, Meghana Chanamolu1, Chad Nieri1,2
1Department of Otolaryngology-Head and Neck Surgery University of Tennessee Health Science Center Memphis Tennessee USA.
OTO open
|April 28, 2025
概括
增加的舌头体积和脂肪是阻塞性睡眠呼吸暂停 (OSA) 的重要危险因素. 这一元分析证实了较大的舌头与OSA严重程度之间的联系,强调了需要进一步研究的必要性.
科学领域:
- 睡眠医学 睡眠医学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 放射学 放射学是一门学科.
背景情况:
- 巨,或扩大的舌头,是阻塞性睡眠呼吸暂停 (OSA) 的已知危险因素.
- 肥胖,舌头脂肪和OSA发展之间的确切关系尚不清楚.
- 了解舌头脂肪如何影响OSA对于有效管理至关重要.
研究的目的:
- 评估舌头脂肪体积与OSA的存在和严重程度之间的相关性.
- 综合现有关于舌头大小对OSA的影响的证据.
主要方法:
- 对2002年9月至2022年间发表的研究进行了系统的文献搜索.
- 一项元分析包括6项病例控制研究,涉及219名OSA患者和133名对照患者.
- 研究被选,数据被提取,质量被评估在一个盲目的,两阶段的过程.
主要成果:
- 患有OSA的患者表现出舌头体积显著增加 (平均差异:19.00厘米3;P <.00001).
- 在OSA患者中也观察到舌头脂肪体积的显著增加 (平均差异:8.04厘米3;P <.00001).
- 包含的研究具有偏差的低至中等风险.
结论:
- 增加的舌头体积和脂肪组织是与OSA相关的显著风险因素.
- 需要进一步的大规模研究来探索舌头脂肪分布以及体重变化对舌头特征和OSA严重性的影响.
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