结肠癌与怀孕的关系
Olivia A Sacks1, Jennifer S Davids1
1Department of Surgery, Boston University School of Medicine, Boston, Massachusetts.
Clinics in colon and rectal surgery
|April 28, 2025
概括
怀孕期结肠直肠癌 (CRC) 正在增加,原因是晚期生育和年轻成年人的发病率增加. 早期诊断和量身定制的治疗对于管理这种罕见但重要的疾病至关重要.
科学领域:
- 在瘤学瘤学.
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 胃肠病学 胃肠病学
背景情况:
- 大肠直肠癌 (CRC) 的发病率在年轻人群中正在增加.
- 妇女正在推迟生育,导致怀孕期间CRC的可能性更高.
- 由于其历史上的稀有性,对怀孕期间的CRC存在有限的数据.
研究的目的:
- 审查当前关于怀孕期间结直肠癌的诊断,检查和治疗的证据.
- 探索在孕妇中诊断CRC的挑战.
- 在怀孕期间诊断CRC后讨论生育方面的考虑.
主要方法:
- 关于怀孕期间结直肠癌现有研究的文献综述.
- 分析包括内镜和计算机断层扫描在内的诊断方式.
- 基于癌症阶段和妊娠期的治疗策略的检查.
主要成果:
- 怀孕期间的CRC往往是晚期诊断的,原因是怀孕期间的症状重叠.
- 怀孕和非怀孕的患者的诊断工作是相似的.
- 治疗决策是个性化的,基于癌症阶段和妊娠期.
结论:
- 怀孕期间结肠直肠癌需要仔细考虑,因为发病率增加和诊断延迟.
- 多学科管理对于最佳结果至关重要.
- 保持生育能力是诊断后解决问题的重要方面.
相关概念视频
Cancer Prevention
6.0K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
6.0K
Tumor Progression
6.1K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
6.1K
Inflammatory Bowel Disease I: Ulcerative Colitis
93
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
93
Assessment of the Rectum and Anus
98
Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
98
Disorders of the Female Reproductive System
204
The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
204
Endoscopic Procedures II: Colonoscopy
26
The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
26


