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Updated: May 10, 2025

Manufacture and Drug Delivery Applications of Silk Nanoparticles
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新型药物输送系统用于对抗H. pylori:一个简短的回顾

M Iman1, S Mirfakhraee2

  • 1Department of Pharmaceutics, Faculty of Pharmacy, Baqiyatallah University of Medical Sciences, Tehran, Iran.

Archives of Razi Institute
|April 28, 2025
PubMed
概括

像纳米粒子这样的新型药物输送系统,为对抗抗生素耐药的Helicobacter pylori (H. pylori) 感染提供了有希望的解决方案,并降低了胃癌的风险. 这些先进的方法提高了治疗效率和目标交付.

关键词:
抗生素耐药性 抗生素耐药性微粒子和纳米粒子的使用新的药物输送系统.黑利哥巴克特皮洛里菌感染.

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The selection of a drug's delivery route depends upon its physicochemical properties, including lipid or water solubility and ionization, as well as the therapeutic requirement, such as immediate or sustained effect. These routes can be divided into three primary categories: enteral, parenteral, and topical.
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the...
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Drug Delivery: Enteral Route

The enteral drug administration involves three primary routes: oral, sublingual, and buccal. Oral ingestion is the most prevalent, safe, economical, and convenient method for drug administration. However, it has certain drawbacks, including limited absorption due to the drug's low water solubility or poor membrane permeability, possible emesis from GI mucosa irritation, destruction of drugs by digestive enzymes or low gastric pH, and irregular absorption along with food or other drugs.
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