转录因子LHX2抑制了出生后哺乳动物大脑皮层中的天体细胞增殖

Archana Iyer1,2, Reanne Fronteiro1, Prachi Bhatia1

  • 1Department of Biological Sciences, Tata Institute of Fundamental Research, Mumbai, India.

Development (Cambridge, England)
|April 28, 2025
PubMed
概括

转录因子LHX2的丧失增加了在皮层上层的天体细胞增殖,并促进了在天体细胞中反应性的分子签名,即使没有受伤. 这突显了LHX2在调节星细胞发育和状态方面的作用.

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