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在土耳其出现的西尼罗病毒感染

Özlem Alhan¹, Meliha Meriç Koç², Ayşe Batırel³

¹Infectious Diseases and Clinical Microbiology, Koç University Hospital, İstanbul, Türkiye. oalhan@kuh.ku.edu.tr.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology

|April 28, 2025

概括

西尼罗河病毒 (WNV) 感染在土耳其在2024年出现了重大爆发. 高龄和二次细菌感染与WNV患者的较高死亡率有关.

科学领域:

医学昆虫学医学昆虫学
传染性疾病传染性疾病
神经学神经学

背景情况:

西尼罗河病毒 (WNV) 是一种蚊子传播的黄病毒,具有神经侵入的潜力.
土耳其在2024年经历了最大的WNV疫情,需要进行详细的临床和流行病学分析.

研究的目的:

描述2024年土耳其爆发期间人类WNV感染的临床和实验室特征.
为了确定WNV病例中死亡率的预测因素.

主要方法:

对11家三级医院51名WNV感染患者的临床数据的回顾性分析.
根据ECDC标准将病例分类为确诊或可能的病例.
多变量逻辑回归用于确定死亡率预测因子的几率比率.

主要成果:

该研究包括51名患者 (平均年龄63.3岁,72.5%是男性).
神经侵入性疾病很普遍 (94.1%),包括脑膜炎 (47%) 和脑炎 (39.2%). 在39.2%的患者中观察到运动障碍.
病例死亡率为17.6%,老年和二次细菌感染被确定为显著的死亡率预测因素.

结论:

2024年的疫情凸显了土耳其越来越多的WNV病例和诊断挑战.
早期诊断和改善的管理对于更好的患者结果至关重要.
建议医疗保健专业人员提高意识,可访问的诊断和快速测试.

关键词:

剧烈的松性麻症剧烈的松性麻症脑炎是一种脑炎.脑膜大脑炎是一种脑膜大脑炎.媒介性疾病媒介性疾病是由载体传播的疾病.西尼罗病毒感染的情况

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