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Updated: May 9, 2025

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Orai1通过调节光滑肌肉细胞表型转换,参与高血压引起的冠状动脉功能障碍

Hao Wang1, Mei-Ying Liang2,3, Yong-Jiang Cai2,3

  • 1Department of Cardiology, the Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
|April 28, 2025
PubMed
概括

高血压通过调节Orai1来损害冠状动脉,这是一种对储存运行入 (SOCE) 至关重要的蛋白质. 这一途径驱动血管光滑肌肉细胞的转化,有助于高血压引起的冠状动脉功能障碍.

关键词:
这里是Orai1 .在VSMCs中.冠状动脉的冠状动脉这种高血压,高血压.自发高血压的老鼠.

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