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Updated: Jun 16, 2026

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潜在的DDI风险评估Vicasinabin与PBPK建模通过整合体外数据的风险评估

Kenichi Umehara1, Neil Parrott1, Andreas Günther1

  • 1Pharmaceutical Sciences, Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.

Clinical pharmacology and therapeutics
|April 28, 2025
PubMed
概括

维卡西纳是炎症性疾病的CB2激动剂,具有可预测的药物相互作用. 基于生理学的药物动力学建模准确评估了其临床药物相互作用风险,证实了其安全性.

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