Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Navigating the Complexity and Heterogeneity of Thrombectomy Decision-Making for Medium-Vessel Occlusion Stroke: Where Do We Go From Here?

Stroke (Hoboken, N.J.)·2026
Same author

Stent retriever-assisted intra-arterial lysis for distal vessel occlusions: a feasible pharmacomechanical rescue strategy.

Journal of neurointerventional surgery·2026
Same author

Physician Approaches to Determining Goals of Stroke Care for Patients Living With Disability or Dementia: Results from the SEED Mixed-Methods Study.

Stroke·2026
Same author

Safety and Efficacy of Nerinetide at Year 1 in Participants Enrolled in ESCAPE-NEXT: A Multicenter, Double-Blind, Randomized Controlled Trial.

Journal of the American Heart Association·2026
Same author

Association of Successful Recanalization and Functional Outcomes in Minor Ischemic Stroke With Proven Occlusion: A Secondary Analysis of TEMPO-2 Trial.

Stroke·2026
Same author

Phase 2 Futility Trials in Alzheimer Disease and Mild Cognitive Impairment: A Cohort Analysis of the ADNI Data Set.

Neurology·2026

相关实验视频

Updated: May 9, 2025

The Impact of Motor Task Conditions on Goal-Directed Arm Reaching Kinematics and Trunk Compensation in Chronic Stroke Survivors
15:00

The Impact of Motor Task Conditions on Goal-Directed Arm Reaching Kinematics and Trunk Compensation in Chronic Stroke Survivors

Published on: May 2, 2021

3.5K

在急性中风试验中减轻和量化桃挑选.

Mayank Goyal1, Aravind Ganesh1

  • 1Departments of Clinical Neurosciences, Community Health Sciences, and Radiology, Calgary Stroke Program, and the Hotchkiss Brain Institute, University of Calgary Cumming School of Medicine, AB, Canada.

Stroke
|April 28, 2025
PubMed
概括
此摘要是机器生成的。

在临床试验中选择性招募患者或挑选桃会损害结果. 本研究确定了病因,检测方法和缓解策略,以提高试验有效性和概括性.

关键词:
临床试验是指临床试验中的临床试验.发生出血 发生出血缺血缺血症是什么意思 缺血缺血症一次性中风中风中风中风中风进行血栓切除术 (thrombectomy).

更多相关视频

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

11.8K
Performing Permanent Distal Middle Cerebral with Common Carotid Artery Occlusion in Aged Rats to Study Cortical Ischemia with Sustained Disability
09:11

Performing Permanent Distal Middle Cerebral with Common Carotid Artery Occlusion in Aged Rats to Study Cortical Ischemia with Sustained Disability

Published on: February 23, 2016

21.4K

相关实验视频

Last Updated: May 9, 2025

The Impact of Motor Task Conditions on Goal-Directed Arm Reaching Kinematics and Trunk Compensation in Chronic Stroke Survivors
15:00

The Impact of Motor Task Conditions on Goal-Directed Arm Reaching Kinematics and Trunk Compensation in Chronic Stroke Survivors

Published on: May 2, 2021

3.5K
Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

11.8K
Performing Permanent Distal Middle Cerebral with Common Carotid Artery Occlusion in Aged Rats to Study Cortical Ischemia with Sustained Disability
09:11

Performing Permanent Distal Middle Cerebral with Common Carotid Artery Occlusion in Aged Rats to Study Cortical Ischemia with Sustained Disability

Published on: February 23, 2016

21.4K

科学领域:

  • 临床试验 临床试验
  • 医学研究方法学 医学研究方法学
  • 医疗保健服务研究 医疗服务研究

背景情况:

  • 连续招募患者对于随机对照试验 (RCT) 的内部和外部有效性至关重要.
  • 试验中的非代表性患者群体,通常是由于选择性招募 (桃挑选),破坏了研究结果的概括性.
  • 在试验环境之外对符合条件的患者进行治疗可能会导致有偏见的参与者选择.

研究的目的:

  • 讨论临床试验中患者桃挑选的问题.
  • 探索有助于桃挑选的因素,包括调查员激励措施.
  • 检查识别和减轻桃挑选的策略,以提高试验有效性.

主要方法:

  • 在临床试验中选择性招募患者的因素的审查.
  • 批判性检查策略,以识别和减轻患者的桃挑选.
  • 提出了一种定量方法,以评估急性中风试验中的桃挑选,将其与不足招聘区分开来.

主要成果:

  • 选择性招聘 (桃挑选) 对随机对照试验的有效性和普遍性构成重大威胁.
  • 研究人员的激励措施 (例如"为我们带来什么"问题) 可能会导致桃挑选.
  • 量化桃挑选对于制定有效的缓解策略至关重要.

结论:

  • 解决患者桃挑选问题对于加强随机对照试验的内部和外部有效性至关重要.
  • 开发和实施量化桃挑选方法将促进解决这一问题的有意义进展.
  • 改进的招聘策略将提高临床试验结果的可靠性和适用性.