在COVID-19大流行期间,急性A型大动脉剖析患者接受手术修复
Yun-Tai Yao1, Chun-Mei Xie2, Hong-Bai Wang1
1Anesthesia Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Beijing, China.
Medicine
|April 28, 2025
概括
急性甲型大动脉剖析 (ATAAD) 患者的手术结果在COVID-19大流行之前和期间都相似. 然而,患有COVID-19的ATAAD患者在紧急手术后面临着明显更高的死亡率和发病率风险.
科学领域:
- 心血管外科心血管外科
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 急性甲动脉解剖A型 (ATAAD) 是一种危及生命的疾病,需要立即进行手术.
- COVID-19大流行严重影响了全球的外科手术实践.
- 疫情对ATAAD手术修复结果的影响以前尚不清楚.
研究的目的:
- 系统地审查和比较COVID-19大流行之前和期间ATAAD患者的手术结果.
- 分析与COVID-19感染同时接受手术的ATAAD患者的结果.
主要方法:
- 一个系统的审查和对比ATAAD手术结果的研究的元分析.
- 关于涉及COVID-19的ATAAD患者的已发表病例的文献综述.
- 搜索了包括PubMed,CNKI,VIP,WANFANG和SinoMed在内的主要数据库,截至2024年1月.
- 利用RevMan进行元分析,估计聚合赔率比率和加权平均差异.
主要成果:
- 在大流行期间接受手术的患者年龄较大,BMI较低,吸烟率较高.
- 在大流行前和大流行后的组中,总体死亡率和发病率是可比的,在大流行期间肺炎发病率增加.
- 在24名COVID-19阳性ATAAD患者中,83.3%的患者康复,但4人死于多器官和呼吸衰竭等并发症.
结论:
- ATAAD手术的住院结果在大流行前和大流行期间基本上保持了可比性.
- 在接受紧急手术的ATAAD患者同时感染COVID-19的死亡率和发病率风险显著增加.
- 研究结果强调了在ATAAD手术规划中考虑COVID-19状态的重要性.
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