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Updated: May 9, 2025

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合成,表征和生物评估新系列的pyrazoline衍生物作为潜在的抗真菌剂

Chandra Shekhar Yadav1,2, Atul Krishna3, Suriya Pratap Singh4

  • 1Department of Chemistry, Integral University, Lucknow, India.

Scientific reports
|April 28, 2025
PubMed
概括

新的罗衍生物显示出强烈的抗真菌活性,可以对抗Candida物种. 化合物4c表现出强大的抑制作用,计算研究揭示了对关键真菌标的双重抑制机制.

关键词:
抗菌的 抗菌的 抗菌的这是一种抗真菌药物.标志性描述 标志性描述与药物相似的情况.分子对接是分子对接.综合合成 综合合成

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The reaction of weakly electrophilic aryldiazonium (also called arenediazonium) salts with highly activated aromatic compounds leads to the formation of products with an —N=N— link, called an azo linkage. This reaction, presented in Figure 1, is known as diazo coupling and occurs without the loss of the nitrogen atoms of the aryldiazonium salt. Highly activated aromatic compounds such as phenols or arylamines favor the diazo coupling reaction. The coupling generally occurs at the...
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