Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Drugs for Treatment of Ulcerative Colitis in IBD01:29

Drugs for Treatment of Ulcerative Colitis in IBD

102
Ulcerative colitis is a chronic inflammatory condition primarily affecting the colon and rectum. The primary drugs used in the treatment of ulcerative colitis are aminosalicylates. They exhibit anti-inflammatory and immunosuppressive properties. They modulate inflammatory mediators and inhibit the activity of nuclear factor κB (NF-κB). Aminosalicylates also reduce inflammation by inhibiting prostaglandin and leukotriene production and decreasing neutrophil chemotaxis and superoxide...
102
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

57
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
57

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Fabrication and evaluation of a bi-layered electrospun polyacrylonitrile/polycaprolactone-chitosan/gelatin/polyethylene oxide nanofibers containing antibiotics and nanoparticles: antibacterial and antibiofilm activity.

Scientific reports·2026
Same author

From Gene Expression to Candidate Biomarkers in Ulcerative Colitis: Aquaporin-9 in Neutrophil Extracellular Traps Formation Pathways.

Iranian journal of medical sciences·2026
Same author

Nanostructured Lipid Carriers Co-Loaded with Doxycycline, Gentamicin, and Thymol for Enhanced Intracellular Antibacterial Activity Against <i>Brucella melitensis</i>.

International journal of nanomedicine·2026
Same author

Bacteriophage therapy against American foulbrood in honey bees: a PRISMA-guided systematic review.

Frontiers in microbiology·2026
Same author

Antibacterial and antibiofilm activities of curcumin-mediated green-synthesised silver nanoparticles against Methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa.

BMC biotechnology·2026
Same author

Management of Diabetic Foot Infections Using Phage Therapy.

Infection and drug resistance·2026

相关实验视频

Updated: May 9, 2025

Quantitative Polymerase Chain Reaction-based Analyses of Murine Intestinal Microbiota After Oral Antibiotic Treatment
08:33

Quantitative Polymerase Chain Reaction-based Analyses of Murine Intestinal Microbiota After Oral Antibiotic Treatment

Published on: November 17, 2018

12.8K

肠道微生物和耐治疗性性结肠炎:使用qPCR的病例对照研究.

Amjad Ahmadi1,2, Leili Shokoohizadeh1,2, Farshad Sheikhesmaili3

  • 1Infectious Disease Research Center, Avicenna Institute of Clinical Sciences, Avicenna Health Research Institute, Hamadan University of Medical Sciences, Hamadan, Iran.

BMC microbiology
|April 28, 2025
PubMed
概括

研究性结肠炎 (UC) 中的肠道微生物组揭示了治疗耐药和新诊断的患者之间的显著差异. 这些微生物组变异可能会影响治疗结果,并指导UC管理的新治疗策略.

关键词:
我们的肠道微生物组.性结肠炎是一种qPCRR 是一个很好的方法.

更多相关视频

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
11:22

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

27.6K
Gastric Mucosa Quantitative Polymerase Chain Reaction Analysis for Detecting Helicobacter pylori and Antibiotic Resistance
05:23

Gastric Mucosa Quantitative Polymerase Chain Reaction Analysis for Detecting Helicobacter pylori and Antibiotic Resistance

Published on: March 7, 2025

226

相关实验视频

Last Updated: May 9, 2025

Quantitative Polymerase Chain Reaction-based Analyses of Murine Intestinal Microbiota After Oral Antibiotic Treatment
08:33

Quantitative Polymerase Chain Reaction-based Analyses of Murine Intestinal Microbiota After Oral Antibiotic Treatment

Published on: November 17, 2018

12.8K
Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
11:22

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

27.6K
Gastric Mucosa Quantitative Polymerase Chain Reaction Analysis for Detecting Helicobacter pylori and Antibiotic Resistance
05:23

Gastric Mucosa Quantitative Polymerase Chain Reaction Analysis for Detecting Helicobacter pylori and Antibiotic Resistance

Published on: March 7, 2025

226

科学领域:

  • 胃肠病学 胃肠病学
  • 微生物学 微生物学
  • 免疫学 免疫学 免疫学

背景情况:

  • 肠道微生物组在性结肠炎 (UC) 的发病和进展中发挥着关键作用.
  • 了解肠道微生物组在耐火性UC中的功能,对于开发有效的治疗策略至关重要.
  • 这项研究调查了不同UC严重程度的患者及其亲属的微生物差异.

研究的目的:

  • 探索肠道细菌在耐火性性结肠炎 (UC) 患者中的作用.
  • 为了比较新诊断的UC患者,耐治疗的UC患者和他们的健康亲属之间的肠道微生物组合.
  • 为了确定与UC治疗反应相关的潜在微生物生物标志物.

主要方法:

  • 一项涉及四组的病例控制研究:新的UC患者 (n=24),耐治疗UC患者 (n=23),新UC患者的亲属 (n=24) 和耐治疗UC患者的亲属 (n=23).
  • 使用定量实时PCR (qPCR) 和培养方法分析了便样本.
  • 通过问卷收集有关益生菌消费和抗生素使用的数据.

主要成果:

  • 在任何组中都没有检测到任何致病细菌.
  • 在特定的微生物群体 (大肠杆菌,Bifidobacterium等) 之间观察到显著的关系. 在治疗耐药性UC患者及其亲属 (组2和4) 中.
  • 在 Lactobacillus ssp., Bifidobacterium ssp. 和 Bacteroides ssp. 中存在显著的差异. 在新诊断的UC患者和耐治疗UC患者 (组1和组2) 之间发现.

结论:

  • 肠道微生物组的组成显著影响性结肠炎的管理.
  • 治疗耐药和新诊断的UC患者之间的微生物组差异为治疗变化提供了洞察力.
  • 研究结果表明,对于UC,基于微生物组的疗法有潜力,包括便微生物组移植 (FMT),益生菌和益生菌.