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推迟血压超标的献血者:是否会降低不良反应的风险?
Catherine Thibeault1, Antoine Lewin1, Isabelle Rabusseau2
1Medical Affairs and Innovation, Héma-Québec, Montréal, Québec City, Canada.
Transfusion
|April 29, 2025
概括
献血血压 (BP) 延期与血管反应 (VVR) 不相关. 取消BP延期并没有增加VVR发生率,支持为献血者进行其去除.
科学领域:
- 血液学 血液学 血液学
- 心血管医学 心血管医学
- 公共卫生 公共卫生
背景情况:
- 血液服务机构经常推迟血液压力 (BP) 读数超出范围的捐赠者.
- 支持BP延期做法的证据是模糊的.
- 血管道反应 (VVR) 是献血中常见的一个问题.
研究的目的:
- 为了评估献血前BP和VVR在献血者之间的关联.
- 为了比较BP推迟撤回之前和之后的VVR率.
主要方法:
- 分析了来自加拿大北克省189,329名捐赠者的532,042份捐赠.
- 在大流行前期 (BP延期) 和大流行后期 (没有BP延期) 的VVR率的比较.
- 根据年龄,性别和捐赠者身份进行统计调整.
主要成果:
- 在低或高的捐赠前BP和VVR的几率之间没有发现显著的关联.
- 在低血压的捐赠者中,VVR的几率比为1.03 (95% CI:0.67-1.63).
- 在高血压的捐赠者中,VVR的几率比为0.96 (95% CI:0.81-1.14).
- 在这两个时期,VVR率保持稳定,约为3.0-3.1%.
结论:
- 捐献前的血压水平与血管血管反应无关.
- 取消BP延期标准并没有导致VVR发病率的增加.
- 这些发现提供了强有力的证据,支持在献血实践中停止BP延期.
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