声学特征独立地与心力衰竭和肺高血压有关
Jaskanwal Deep S Sara1, Keiko Ishikawa2, Yan Li3
1Department of Cardiovascular Medicine, Mayo College of Medicine, Rochester, Minnesota, USA.
语音分析显示,心力衰竭 (HF) 和肺高血压 (PH) 患者的语音节奏较慢. 声学特征,如塞普斯特拉峰值突出也不同,这表明这些条件的非侵入性查的潜力.
科学领域:
- 心脏病学 心脏病学
- 肺部病理学 肺部病理学
- 语音科学 语言科学
背景情况:
- 语音的声学分析以前已经确定了不补偿的急性心力衰竭 (HF).
- 语音速率 (SR) 和头顶峰突出度 (CPP) 是已知的声学特征.
- 没有研究SR和CPP与慢性稳定高血压和/或肺高血压 (PH) 的相关性.
研究的目的:
- 调查声学特征 (SR,CPP) 与慢性稳定心力衰竭 (HF) 和肺高血压 (PH) 之间的关联.
- 探索声学分析在区分HF,PH和对照组的有用性.
主要方法:
- 2,153名诊所外患者进行了HF和/或PH评估,提供了语音录音.
- 提取了声学特征,包括语音速率 (SR) 和发声 (CPP-V) 和所有语音 (CPP-All) 的头顶突出度 (CPP).
- 线性回归模型评估了声学特征与疾病状态 (HF,PH或没有疾病) 之间的关联.
主要成果:
- 与对照人群相比,只有PH,只有HF和PH的HF患者的说话率 (SR) 显著降低.
- 发声语音 (CPP-V) 和所有语音 (CPP-All) 的 Cepstral 峰值突出也显示了与对照组相比,PH患者的显著差异.
- 经过调整后的分析在考虑年龄和性别后证实了这些显著的关联.
结论:
- 在患有慢性稳定性HF,PH或两者的患者中,与没有这些疾病的患者相比,说话率显著降低.
- 在PH患者中,塞普斯特拉的峰值突出度也显著不同.
- 声学分析显示出作为查和区分慢性稳定HF和PH的非侵入性方法的希望.
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