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Updated: Jun 12, 2025

In Vivo Osteo-organoid Approach for Harvesting Therapeutic Hematopoietic Stem/Progenitor Cells
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八度结合转录因子4在60Co辐射后通过NF-κB信号通路抑制HSC功能

Wenjing Yang1, Xiaoe Jin2, Chao Chen1

  • 1Laboratory Animal Science Department, Basic Medical School, Naval Medical University, Shanghai, China.

Radiation research
|April 29, 2025
PubMed
概括

八合体结合转录因子4 (Oct4) 在辐射诱导的骨髓损伤中起着关键作用. 抑制Oct4或核因子kappa-B (NF-κB) 保护造血干细胞,并改善辐射后的存活率.

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