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Updated: May 21, 2025

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甘氨基化通过中断模糊相互作用来削弱Toxoplasma gondii中的Skp1同质化

Donovan A Cantrell, Ramona J Bieber Urbauer, Hyun W Kim

    Biochemistry
    |April 29, 2025
    PubMed
    概括

    在Toxoplasma gondii中Skp1的糖化削弱了通过破坏失调的C末端区域来削弱同质化. 这种干扰释放了Skp1用于F盒蛋白结合,这对于E3无素酶功能至关重要.

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