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Updated: May 9, 2025

Preparation and Culture of Myogenic Precursor Cells/Primary Myoblasts from Skeletal Muscle of Adult and Aged Humans
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Preparation and Culture of Myogenic Precursor Cells/Primary Myoblasts from Skeletal Muscle of Adult and Aged Humans

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干扰素-γ在免疫肌肉病变中引起肌原细胞功能障碍和衰老

Cyrielle Hou1, Baptiste Periou1,2,3, Marianne Gervais1

  • 1Paris Est Créteil University, INSERM, IMRB U955-Team Relaix, F-94010 Créteil, France.

Brain : a journal of neurology
|April 29, 2025
PubMed
概括

干扰素- (IFNγ) 通过损害肌肉干细胞功能和促进衰老,驱动免疫肌肉病变中的肌肉缩. 像鲁克索利提尼布这样的JAK1/2抑制剂在恢复肌肉健康方面表现有希望,并可能为包括体肌炎提供新的治疗方法.

关键词:
IFNγ IFNγ 的意思是这就是JAK-STAT.包容体肌肉炎 (IBM) 是一个疾病.炎症性肌肉病变症 炎症性肌肉病变症肌肉发育 (myogenesis) 是一个过程.卫星细胞 卫星细胞卫星细胞

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