齐甘可对慢性心力衰竭和抑郁症结合的影响
Ying Wang1, Jun Wang2, Wang Lv1
1Department of Chinese Medicine, Cangzhou Central Hospital, Cangzhou, Hebei, China.
Frontiers in cardiovascular medicine
|April 29, 2025
概括
传统中医药Zhigancao,在加入标准治疗时,改善了慢性心力衰竭和抑郁症患者的治疗结果. 这种综合方法增强了心脏功能,减少了炎症,改善了生活质量.
科学领域:
- 心脏病学 心脏病学
- 精神病学是一个精神病学.
- 综合医学是一个整体的医学.
背景情况:
- 慢性心力衰竭 (CHF) 和抑郁症经常并存,创造了一个复杂的临床挑战,症状相互恶化.
- 管理这种双重状况需要综合治疗策略,解决身体和心理方面的问题.
研究的目的:
- 为了评估Zhigancao的疗效,一个传统的中医药,作为一个辅助治疗患者的心脏衰竭和抑郁症.
- 评估Zhigancao对临床疗效,心脏功能,炎症标志物,抑郁症状和生活质量的影响.
主要方法:
- 一项随机对照试验,涉及122名心血管衰竭和抑郁症患者.
- 患者被分配到对照组 (标准的西方治疗) 或观察组 (标准的西方治疗加上紫金) 中.
- 测量结果包括临床疗效率,左心室喷射率 (LVEF),炎症标志物 (NT-proBNP,MMP-9,hs-CRP),抑郁症得分和生活质量.
主要成果:
- 与对照组相比,Zhigancao蒸组的整体临床疗效率明显更高.
- 观察到心脏功能有所改善,由左心室喷射率 (LVEF) 的增强表明.
- 炎症标志物 (NT-proBNP,MMP-9,hs-CRP) 和抑郁症状显著减少,观察组的生活质量明显改善.
结论:
- 齐冈可作为慢性心力衰竭与抑郁症相结合的患者的辅助疗法,显示出显著的治疗益处.
- 这种传统中医的方法提供了一个整体的策略,有效地改善心血管健康和心理健康.
- 这些发现支持将Zhigancao融入常规治疗方案中,用于管理复杂的心血管衰竭和并发性抑郁症病例.
相关概念视频
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System
302
The activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) contributes to cardiac remodeling, and inhibiting the RAAS is a pharmacological target in heart failure management. As a result, neurohumoral modulation is a crucial treatment principle for managing heart failure. This approach involves using medications like ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), β-blockers, mineralocorticoid receptor antagonists (MRAs), and neutral...
302
Heart Failure Drugs: Diuretics
277
Heart failure and kidney perfusion are interconnected in a complex way. Reduced renal perfusion and venous congestion are two significant factors that contribute to renal dysfunction in heart failure. The kidneys, primarily responsible for fluid balance in the body, are adversely affected due to compromised cardiac output and increased venous pressure. In response to reduced renal perfusion, the kidneys activate neurohumoral mechanisms to restore balance. However, these mechanisms can be...
277
Heart Failure Drugs: Inotropic Agents
401
Positive inotropic agents are commonly used as the first line of treatment for heart failure. One such agent is digoxin, derived from the genus Digitalis, which has been known for centuries but effectively utilized since 1785. However, these cardiac glycosides can have potentially toxic effects due to their mechanism of action, which involves inhibiting Na+/K+-ATPase and increasing contractility. Digoxin is absorbed orally and distributed in various tissues, including the CNS. It has a long...
401


