高甘油三指数与高甘油三指数与高甘油三指数与高甘油三指数与高甘油三指数之间的关联在接受皮肤冠状动脉干预的高甘油三患者中
Yichuan Wang1, Yanfeng Lu1, Shanshan Gao1
1Department of Cardiovascular Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Frontiers in endocrinology
|April 29, 2025
概括
甘油三糖指数 (TyG) 预测了在接受药物排泄支架穿皮冠状动脉干预 (DES-PCI) 的高甘油三血症患者中发生的重大心脏和脑血管不良事件 (MACCE). 高的TyG指数表明MACCE的风险更高.
科学领域:
- 心脏病学 心脏病学
- 代谢综合征是代谢综合征的一种.
- 干预心脏病学 干预心脏病学
背景情况:
- 甘油三糖指数 (TyG) 是心血管疾病中胰岛素耐药性的标志物.
- 它在接受DES-PCI的高甘油三血症患者的预后价值需要进一步研究.
研究的目的:
- 调查Tyg指数和MACCE在接受DES-PCI的高甘油三血症患者之间的关联.
- 评估TyG指数作为这个特定患者群体的预后标记.
主要方法:
- 对2250名患者的回顾性分析,其中813名患有高甘油三血症的患者接受了DES-PCI.
- 卡普兰-梅尔曲线和受限立方斜线分析,以评估TyG指数和MACCE之间的关系.
- 考克斯回归和ROC分析以确定预测因素和切割值.
主要成果:
- TyG指数是MACCE的独立预测指标 (HR 1.53).
- 9.19的TyG指数截止值确定了患有MACCE,MACE,重复血管化和全因死亡风险显著更高的患者.
- 在TyG指数和MACCE风险之间观察到线性关系.
结论:
- 高的TyG指数与DES-PCI后的高甘油三患者的MACCE风险增加有关.
- 泰格指数显示,它有可能成为这个患者群体的有价值的预后工具.
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