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Updated: May 9, 2025

Sample Preparation to Bioinformatics Analysis of DNA Methylation: Association Strategy for Obesity and Related Trait Studies
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Sample Preparation to Bioinformatics Analysis of DNA Methylation: Association Strategy for Obesity and Related Trait Studies

Published on: May 6, 2022

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多基因分数捕捉了脂肪-心脏代谢风险因子关系的遗传修饰

Kenneth E Westerman1,2,3, Julie E Gervis2,3,4, Luke J O'Connor5,6

  • 1Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, Boston, MA, USA.

medRxiv : the preprint server for health sciences
|April 29, 2025
PubMed
概括

这项研究引入了开发多基因分数 (PGS) 的新框架,可以预测个人对干预措施的反应. 相互作用多基因评分 (iPGS) 在识别身体质量指数和心脏代谢风险因素之间的关系中的遗传修饰方面最有效.

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