口香糖与微信增强指令对便秘患者的肠道准备的影响:一项随机对照试验
Cong Gao1, Deli Zou1, Weiyi Wang1,2,3
1Department of Gastroenterology, General Hospital of Northern Theater Command, Shenyang, Liaoning, P. R. China.
Gastroenterology report
|April 29, 2025
概括
在接受结肠镜检查的便秘患者中,口香糖和微信指令并没有改善肠道准备质量. 然而,这种综合方法导致恶心发病率显著增加.
科学领域:
- 胃肠病学 胃肠病学
- 临床试验 临床试验
- 医疗干预 医疗干预
背景情况:
- 便秘患者经常经历肠道准备质量差以及肠道运动功能障碍.
- 用口香糖刺激肠道机动性和增强指令可以改善肠道准备.
- 研究新的策略对于优化这组患者的结肠镜准备至关重要.
研究的目的:
- 评估将口香糖与微信增强指令相结合的疗效,以改善便秘患者的肠道准备质量.
- 评估这项干预措施对腺瘤和/或多检测率 (ADR/PDR) 的影响.
- 为了比较干预和对照组之间的程序时间和不良事件.
主要方法:
- 一个单中心,随机对照试验与115名便秘患者进行.
- 干预组接受了聚乙烯糖醇 (PEG),PEG摄入后口香糖,以及微信指令.
- 对照组仅接受PEG;肠道准备质量和ADR/PDR进行了比较.
主要成果:
- 两组之间没有观察到足够的肠道准备或波士顿肠道准备量表得分的统计学上显著差异.
- 在微信指令 (CGW) 的口香糖和对照组中,腺瘤和/或息肉检测率和息肉数量相似.
- 与对照组相比,CGW组报告的恶心发生率明显高 (33.3%对16.4%,P=0.036).
结论:
- 将口香糖与微信增强指令相结合并不能改善便秘患者结肠镜检查的肠道准备质量.
- 这种干预策略与恶心发病率的增加有关.
- 可能需要进一步的研究,以探索替代方法,以提高这种人群的肠道准备.
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