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Updated: May 13, 2025

Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions
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Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions

Published on: January 26, 2024

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结构导向的泛特异性T细胞受体--主要基因相容性复杂相互作用预测.

Letao Gao1, Yumeng Zhang2, Fang Ge3

  • 1School of Computer Science and Engineering, Nanjing University of Science and Technology, 200 Xiaolingwei, Nanjing 210094, China.

Journal of chemical information and modeling
|April 29, 2025
PubMed
概括

我们开发了计算模型来预测T细胞受体 (TCR) 与-MHC复合体的相互作用,进步了我们对适应性免疫的理解. 这些模型准确地预测了绑定和接触点,为TCR识别机制提供了新的见解.

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