左心房大小和左心房体积指数作为心房高频发作预测因素
Phuuwadith Wattanachayakul1,2, Thitiphan Srikulmontri1,2, Narathorn Kulthamrongsri3
1Department of Medicine, Jefferson Einstein Hospital, Philadelphia, Pennsylvania, USA.
Pacing and clinical electrophysiology : PACE
|April 29, 2025
概括
心房高频发作 (AHRE) 与左心房大小的增加有关. 患有AHRE的患者显示左心脏直径和体积指数增加,这表明形态学影响心脏事件.
科学领域:
- 心脏病学 心脏病学
- 心声回声图 (Echocardiography) 是一种心声回声图.
- 电子生理学 电子生理学
背景情况:
- 高心房发作率 (AHRE) 与不良的心血管结果相关,包括中风和死亡率.
- 人们正在寻找AHRE的预测因子,但左心房形态学的作用还不清楚.
研究的目的:
- 调查左心房形态与AHRE发生之间的关联.
- 为了确定左心房直径和体积指数是否预测没有先前心房的患者的AHRE.
主要方法:
- 来自MEDLINE和EMBASE的18项队列研究的系统审查和元分析.
- 左心房形态通过左心房直径 (LAD) 和左心房体积指数 (LAVI) 通过心声学评估.
- 使用通用逆方差方法计算的聚合平均差异.
主要成果:
- 患有AHRE的患者表现出明显更大的左心脏直径 (平均差异:2.19毫米) 和LAVI (平均差异:4.88毫升/米2).
- 对LAD和LAVI差异的统计学意义得到证实 (p < 0.001).
- 观察到异质性 (LAD 的I2=80%,LAVI 的I2=55%).
结论:
- 左心脏直径增加和LAVI与AHRE的存在有关.
- 左心房形态可能是AHRE发展的重要因素.
- 需要进一步的研究来阐明因果机制.
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