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Updated: May 15, 2025

Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
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乙基酸合成库尔库明模仿剂:替代剂允许在细胞毒性和细胞保护性活动之间切换

Valeria Romanucci1, Rita Pagano1, Solveigh C Koeberle2,3

  • 1Department of Chemical Sciences, University of Napoli Federico II, Via Cintia 4, 80126 Naples, Italy.

Antioxidants (Basel, Switzerland)
|April 29, 2025
PubMed
概括

新型黄素模仿剂,以乙酸为基础的黄素模仿剂 (EPs) 被合成以增强抗癌和神经保护性质. EP4通过细胞亡表现出强烈的癌细胞毒性并抑制E1酶,而EP2具有抗氧化和抗粉胺聚合效应.

关键词:
阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.灭症 (apoptosis) 是一种死亡的过程.癌症 癌症 癌症 癌症 癌症黄素模仿的是黄素.铁性化 (ferroptosis) 是一种氧化应激是一种氧化应激.

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