单独接种流感疫苗或接种COVID-19疫苗后,月经周期长度发生变化
Emily R Boniface1,2, Blair G Darney1,2,3, Agathe van Lamsweerde4
1Department of Obstetrics and Gynecology, Oregon Health & Science University, Portland.
JAMA network open
|April 29, 2025
概括
用或不用COVID-19疫苗接种流感疫苗与月经周期长度的轻微暂时变化有关. 这些变化在接下来的周期中得到解决,为接种疫苗的人提供了保证.
科学领域:
- 生殖健康 生殖健康
- 疫苗学 疫苗学 疫苗学
- 流行病学 流行病学
背景情况:
- 接种COVID-19疫苗与月经干扰有关,但对其他疫苗的数据有限.
- 了解疫苗对月经健康的影响对于患者咨询和解决犹至关重要.
研究的目的:
- 调查流感疫苗接种与月经周期长度变化之间的关联.
- 为了评估同时接种COVID-19疫苗是否会改变这种关联.
主要方法:
- 全球回顾性队列研究利用来自数字节育应用程序的潜在月经周期数据.
- 包括1501名 (18-45岁) 没有荷尔蒙避孕药和定期周期的个人.
- 分析了单独接种流感疫苗或使用COVID-19疫苗后的月经周期长度变化.
主要成果:
- 流感疫苗接种 (单独或与COVID-19疫苗接种) 显示平均周期长度 (0.40-0.49天) 的小而暂时增加.
- 在单独接种流感疫苗和联合接种疫苗组之间,没有观察到周期长度变化的显著差异.
- 月经周期的变化是暂时的,在疫苗接种后的周期中长度恢复到基线;在卵泡阶段发生了变化.
结论:
- 流感疫苗,有或没有COVID-19疫苗,与月经周期长度的轻微暂时变化有关.
- 这些发现可以帮助临床医生解决患者对疫苗接种潜在月经不良影响的担忧.
- 观察到的变化是暂时的,并没有影响整体周期规律.
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