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相关概念视频

Glaucoma: Overview01:25

Glaucoma: Overview

481
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
481
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

368
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
368

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Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
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心率变化 时间域分析 跨青光眼子类型

Yuto Yoshida1, Hinako Takei1, Misaki Ukisu1

  • 1Department of Ophthalmology, Shimane University Faculty of Medicine, Izumo 693-8501, Japan.

Biomedicines
|April 29, 2025
PubMed
概括

心率变化 (HRV) 在各类青光眼亚型之间有所不同,除皮青光眼与初级开角青光眼相比,表现出较低自主神经系统 (ANS) 功能. 眼内压与HRV变化有关.

科学领域:

  • 眼科医生 眼科 眼科
  • 心脏病学 心脏病学
  • 自主神经科学 自主神经科学

背景情况:

  • 玻璃眼和自主神经系统 (ANS) 功能之间的关系尚未完全理解.
  • 主要开角青光眼 (POAG) 和脱皮青光眼 (EXG) 有不同的病理,可能会以不同的方式影响ANS功能.

研究的目的:

  • 调查青光眼亚型 (POAG,EXG) 与时间域心率变化 (HRV) 参数之间的关联.
  • 为了在青光眼患者和对照者之间比较HRV参数,包括正常与正常间隔的标准偏差 (SDNN),连续差异的平方根平均值 (RMSSD) 和R-R间隔的变化系数 (CVRR).

主要方法:

  • 包括809名POAG,EXG和对照患者的809只眼睛.
  • 测量HRV使用指尖肌造影.
  • 分析了时间域HRV参数 (SDNN,RMSSD,CVRR) 并进行了线性回归.

主要成果:

  • 在两组中观察到CVRR的显著差异 (p=0.010).
  • 与初级开角青光眼 (POAG) 患者相比,剥皮青光眼 (EXG) 患者的SDNN和CVRR显著降低 (p=0.0156,p=0.0037).
  • 在多变量分析中,最高眼内压 (IOP) 与CVRR显著相关.
关键词:
自主神经系统自主神经系统脱皮 玻璃眼 玻璃眼 玻璃眼眼内压力 眼内压力主要的开放角光眼 (Glaucoma)时间域心率波动的时间域心率波动

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相关实验视频

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Published on: May 25, 2020

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结论:

  • HRV参数可能表明自主神经系统的变化,具体针对不同的青光眼亚型.
  • 研究结果表明,在POAG和EXG中存在不同的ANS概况,可能与眼内压力有关.