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Updated: May 15, 2025

Pooled shRNA Library Screening to Identify Factors that Modulate a Drug Resistance Phenotype
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B细胞激活因子诱导毛细胞白血病变体的耐药性

Claire Fritz1, Daniel Feinberg1, Akshaya Radhakrishnan2

  • 1Department of Pathology, Case Western Reserve University, Cleveland, OH 44106, USA.

Biomedicines
|April 29, 2025
PubMed
概括

B细胞激活因子 (BAFF) 通过激活非经典核因子kappa B (NF-κB) 途径,促进毛细胞白血病变体 (HCL-v) 的化学抵抗. 阻断BAFF可能会改善抗HCL-v患者的纯氨酸核酸类比 (PNA) 治疗效果.

关键词:
巴夫 (BAFF) 是一个巴夫.在这里,HCL是HCL.在白血病中,白血病.化疗保护 化疗保护化学电阻是一种化学电阻.药物耐药性 耐药性 药物耐药性毛发细胞白血病的发生.

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