美国成年人心血管疾病的趋势和差异与代谢功能障碍相关的脂肪性肝病
Yanbing Zhang1, Xinge Zhang2, Chuiguo Huang2
1Department of Hepatobiliary Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Biomedicines
|April 29, 2025
概括
30年来,心血管疾病 (CVD) 患病率在患有代谢功能障碍相关的脂肪性肝病 (MASLD) 的美国成年人中翻了一番. 差距突出了针对这个不断增长的人口的有针对性的预防和查策略的需要.
科学领域:
- 心脏病学 心脏病学
- 肝病学 肝病学是一种肝病学.
- 公共卫生 公共卫生
背景情况:
- 与代谢功能障碍相关的脂肪性肝病 (MASLD) 是一个越来越令人担忧的问题.
- 心血管疾病 (CVD) 是MASLD患者死亡的主要原因.
- 了解MASLD群体内心血管疾病的趋势和差异至关重要.
研究的目的:
- 分析美国成年人中心血管疾病 (CVD) 患病率的趋势和差异,这些人患有代谢功能障碍相关的脂肪性肝病 (MASLD).
- 确定与MASLD和CVD相关的主要死亡原因和风险因素.
主要方法:
- 国家健康和营养检查调查 (NHANES) III (1988-1994) 和NHANES 2017-2020数据的横截面分析.
- 使用临床概况和肝脏超声波检查进行MASLD鉴定,但不包括其他肝脏疾病.
- 在MASLD个体中估计心脏病发病率,并计算与没有MASLD的人相比患病率的比率.
主要成果:
- 在2017-2020年,MASLD影响了31.2%的美国成年人 (6190万).
- 在MASLD个体中,心脏病发病率从8.7% (NHANES III) 翻了一番,达到17.0% (2017-2020).
- 在老年人,非西班牙裔白人和更高的社会经济群体中,增幅显著,在年轻人中差异更为明显.
结论:
- 观察到,在患有MASLD的美国成年人中,心脏病发病率在30年内显著增加.
- 心血管疾病发病率的社会人口差异强调了针对性公共卫生干预措施的必要性.
- 有针对性的查,预防和政策措施对于解决MASLD人口心血管健康差距至关重要.
更多相关视频
08:41Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease
Published on: March 24, 2023
1.0K
07:12Author Spotlight: Analysis of Fluorescent-Stained Lipid Droplets with 3D Reconstruction for Hepatic Steatosis Assessment
Published on: June 2, 2023
6.0K
相关概念视频
Overview of Lipid Metabolism
870
Lipid metabolism is a crucial process in the human body that involves the synthesis and degradation of lipids. This process is essential for energy production, cell membrane formation, and hormone production, among other functions.
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
870
Diseases of the Liver and Gallbladder
363
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
363
Cholesterol: Significance and Regulation
461
Although not a source of energy, cholesterol plays a significant role as a foundational structure for bile salts, steroid hormones, and vitamin D, as well as being a crucial component of plasma membranes. Approximately 15% of blood cholesterol is derived from our diet, with the remainder synthesized from acetyl CoA by the liver and intestines. Cholesterol is eliminated from the body through its conversion into bile salts, which are eventually discarded in the feces.
Considering cholesterol and...
Considering cholesterol and...
461
Ultrasound II: Endoscopic Ultrasound and FibroScan
59
Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
Endoscopic Ultrasound (EUS):
Endoscopic Ultrasound (EUS):
59
Obesity
347
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
347
Liver Physiology
391
The liver, an essential organ in the human body, performs over 200 vital functions that can be broadly categorized into metabolic, hematological, endocrine regulation, and bile production.
Metabolic Regulation:
The liver is the central organ involved in regulating blood composition. It stabilizes blood glucose levels, maintaining them within the range of 70–110 mg/dL. When these levels drop, the liver breaks down glycogen reserves and releases glucose into the bloodstream. It can...
Metabolic Regulation:
The liver is the central organ involved in regulating blood composition. It stabilizes blood glucose levels, maintaining them within the range of 70–110 mg/dL. When these levels drop, the liver breaks down glycogen reserves and releases glucose into the bloodstream. It can...
391
