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Updated: May 9, 2025

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骨髓瘤患者的T细胞表型和克隆性变化,总体存活时间短

Alenka Djarmila Behsen1, Esten Nymoen Vandsemb1, Tobias Schmidt Slørdahl1

  • 1Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.

JCI insight
|April 29, 2025
PubMed
概括

与长期幸存者相比,存活时间较短的多发性骨髓瘤患者显示出显著的免疫系统变化,包括较少的T细胞和更多的Tregs. 诊断时CD8+T细胞的PD-1较高预测总生存时间较短.

关键词:
癌症 癌症 癌症 癌症血液学 血液学 血液学免疫学 免疫学 免疫学在瘤学瘤学.T细胞受体受体的 T 细胞受体.在T细胞,T细胞.

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