一项前性研究,比较腰围和BMI作为损伤进展的预测指标
Jou-Yin Chen1, Yukiko Wagatsuma2
1Department of Clinical Trials and Clinical Epidemiology, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan.
PloS one
|April 29, 2025
概括
腰围 (WC) 预测男性脏损伤的进展,但体重指数 (BMI) 仍然是两性可靠的指标. 保持健康的BMI和WC对于脏健康至关重要.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 公共卫生 公共卫生
- 内分泌学 在内分泌学.
背景情况:
- 慢性病 (CKD) 是不可逆转的,影响生活质量.
- 肥胖,通常用体重指数 (BMI) 来衡量,是已知的CKD进展的风险因素.
- 腰围 (WC),反映腹部脂肪,被提出作为一种替代的肥胖指标.
研究的目的:
- 调查腰围 (WC) 是否可以预测损伤的进展.
- 将WC的预测能力与体重指数 (BMI) 进行比较.
主要方法:
- 对4129个正常功能个体 (2016-2019) 的前性研究.
- 收集了BMI,WC,生活方式和并发症的基线数据.
- 在2023年之前监测损伤进展的参与者,分析WC和BMI的关联.
主要成果:
- 在男性中,WC表明损伤进展的风险更高 (HR=1.01-1.39).
- 这些关联在女性中没有显著意义.
- 在对BMI进行调整后,WC的预测值下降.
- 超重男性 (BMI ≥25 kg/m2) 的风险显著增加 (HR = 1.69).
结论:
- 腰围是男性损伤进展的重要因素.
- 体重指数仍然是损伤的可靠预测指标.
- 保持健康的BMI和WC对于降低CKD进展风险至关重要.
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