通过传感器贴片进行非侵入性血液动力学评估:PATCHWRK (无线心肌病追踪可移植技术) 研究
Zak Loring1, Nicholas B Bolus2, F Brennan Torstrick2
1Division of Cardiology, Department of Medicine, Duke University, Durham, North Carolina, USA; Duke Clinical Research Institute, Durham, North Carolina, USA.
JACC. Advances
|April 29, 2025
概括
一个新的SANSA传感器贴片准确地测量了心脏计时间隔,如透心填充时间 (DFT),有助于早期检测心脏病. 这种可穿戴技术为纵向患者监测提供了一个有希望的替代方案.
科学领域:
- 心脏病学 心脏病学
- 生物医学工程 生物医学工程
- 医疗器械 医疗器械
背景情况:
- 心声计时间隔提供了对临床前心脏功能障碍的预后见解.
- 缩短的透静填充时间 (DFT) 与左捆支部阻塞患者心肌病风险有关.
- 由于专用设备的需要,目前的心声回声学限制阻碍了纵向评估.
研究的目的:
- 为了评估多式传感器补丁 (SANSA) 来评估心脏计时间隔.
- 具体评估的是透缩填充时间 (DFT),预喷射期 (PEP) 和左心室喷射时间 (LVET).
主要方法:
- 预计将招募50名接受心声回声扫描的患者.
- 同时记录使用SANSA贴片和心声回声.
- 通过连续波,脉冲波和组织多普勒成像,以及SANSA的心电图,地震图和心电图数据分析计时间隔.
- 使用类内相关系数 (ICC) 评估协议.
主要成果:
- 从92%的患者 (46/50) 获得的可分析数据.
- SANSA显示了对心声回声学的高度一致:DFT的ICC为0.92,PEP为0.74,LVET为0.76.
- SANSA衍生的间隔与不同回声心脏图视图之间获得的间隔相似.
结论:
- SANSA贴片提供了心脏计时间隔的准确测量,可与心声回声相提并论.
- 这种可穿戴技术可以通过纵向监测提前检测心肌病.
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