运动可以改善心肌变形,但不能改善早产成人心脏结构:一项随机临床试验
Winok Lapidaire1, Afifah Mohamed2, Wilby Williamson3
1Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.
JACC. Advances
|April 29, 2025
概括
有氧运动改善了早产成人的心脏功能,但没有改变心脏结构. 这一发现凸显了运动对早产儿血压升高的益处.
科学领域:
- 心脏病学 心脏病学
- 运动生理学 运动生理学
- 新生儿科学 新生儿科学
背景情况:
- 过早出生 (<37周妊娠) 个体可能具有不良的心脏表型,随着血压升高而恶化.
- 了解早产的长期心脏影响和干预措施的影响对于心血管健康至关重要.
研究的目的:
- 为了调查早产儿和早产儿在16周的有氧运动干预后是否表现出类似的心脏结构和功能重塑.
- 为了比较有氧运动对早产儿心脏参数的影响,与患有高血压的成年人相比.
主要方法:
- 一项随机对照试验,涉及203名患有高血压或第一阶段高血压的成年人 (18至35岁).
- 参与者被随机分配到16周的有氧运动干预或对照组.
- 心血管磁共振成像 (CMR) 用于评估干预前后的左心室和右心室 (LV和RV) 结构和功能.
主要成果:
- 在按期出生的参与者中,有氧运动导致LV质量与终端透析体积比率的减少和VR中风体积指数的增加.
- 运动组中早产儿的参与者在LV周围应变和RV全球纵向应变方面有所改善,但心脏结构没有显著变化.
- 在早产的参与者中没有观察到任何显著的心脏结构变化,在早产的参与者中也没有观察到任何显著的心肌变形效应.
结论:
- 有氧运动训练在早产成年人中改善心肌功能,但不会显著改变心脏结构.
- 这些发现表明,虽然运动有益于心脏功能,但在早产和满产的个体之间,结构性适应可能会有所不同.
更多相关视频
07:55Echocardiographic Characterization of Left Ventricular Structure, Function, and Coronary Flow in Neonate Mice
Published on: April 7, 2022
2.7K
09:15Displacement Analysis of Myocardial Mechanical Deformation DIAMOND Reveals Segmental Heterogeneity of Cardiac Function in Embryonic Zebrafish
Published on: February 6, 2020
4.9K
相关概念视频
01:20Exercise and Cardiovascular Response
650
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
650
01:17Exercise and Cardiac Output
708
Regular physical activity is essential for maintaining cardiovascular health, with aerobic exercises being particularly effective. According to the American Heart Association, 150 minutes of moderate to intense aerobic exercise per week is recommended for a healthy heart. Aerobic activities may include brisk walking, running, bicycling, cross-country skiing, and swimming, ideally performed three to five times per week.
Sustained exercise increases the muscles' oxygen demand, which can be...
Sustained exercise increases the muscles' oxygen demand, which can be...
708