用 pembrolizumab 治疗宫癌复发的使用模式
Yongmei Huang1, Katherine Yoh1, Elizabeth A Szamreta2
1Columbia University Vagelos College of Physicians and Surgeons, Department of Obstetrics and Gynecology, New York, NY.
概括
对复发性子宫癌的 pembrolizumab 使用正在增加,但有限. 虽然没有增加医疗保健访问,但它显著提高了治疗成本,表明需要优化治疗方法.
科学领域:
- 在瘤学瘤学.
- 医疗保健服务研究 医疗服务研究
背景情况:
- 复发性宫癌的治疗正在发展.
- 了解真实世界的 pembrolizumab (免疫疗法) 使用是至关重要的.
研究的目的:
- 评估pembrolizumab在复发性子宫癌中的实际使用情况.
- 分析相关的医疗保健利用率和成本.
主要方法:
- 使用Merative MarketScan研究数据库,从2017年至2022年对2727名患者进行了回顾性分析.
- 在第一次复发时检查了全身疗法使用,包括pembrolizumab.
- 用和不用 pembrolizumab 的患者之间的医疗保健利用和成本的比较.
主要成果:
- 布罗利祖马布在接受复发治疗的患者中使用了12.1%.
- 布罗利祖马布的使用与最近的复发,年龄较大和先前的化疗相关.
- 佩布罗利祖马布的使用并没有增加住院或急救诊所的访问,但显著增加了总和化疗费用.
结论:
- 基于的化疗仍然是复发性宫癌的主要治疗方法.
- 布罗利祖马布的使用正在增长,但有限,这表明与指导方针推的临床验证疗法保持一致的机会.
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