基于深度学习的自动左心房细分和实时相对照MRI在心房的患者的流量量化
Justin Baraboo1,2,3, Amanda DiCarlo4, Haben Berhane5,4
1Northwestern Biomedical Engineering, Chicago, Illinois, USA. Justin.Baraboo@northwestern.edu.
The international journal of cardiovascular imaging
|April 29, 2025
概括
一个新的卷积神经网络 (CNN) 自动化左心房 (LA) 流量量化心房 (AF) 患者使用实时2D相对比MRI. 这种人工智能工具显著减少了分析时间,同时保持了与人类分析相当的准确性.
科学领域:
- 心血管成像 - 心血管成像
- 人工智能在医学中的应用
- 医学图像分析 医学图像分析
背景情况:
- 实时二维相位对比 (RTPC) MRI对于量化心房动 (AF) 患者的血流至关重要.
- 传统分析涉及耗时的左心室 (LA) 手动轮,跨越多个心脏时间框架.
- 这种手动过程在临床工作流程和研究中构成了瓶.
研究的目的:
- 开发和验证一个卷积神经网络 (CNN) 用于完全自动化的LA流量量化使用RTPCMRI数据.
- 与半人工方法相比,评估CNN在轮和流量测量的准确性和可靠性.
- 在AF患者的背景下评估CNN的表现,考虑到心率变化.
主要方法:
- 一个CNN在15307个半手动LA轮上进行了训练和验证,这些轮来自44名AF患者的RTPCMRI扫描.
- 性能使用子得分 (DSC) 和豪斯多夫距离 (HD) 来评估轮准确度.
- 流量量化指标,包括静止,速度和净流量,与半人工分析进行了比较.
主要成果:
- 美国有线电视新闻网 (CNN) 获得了与人类观察者之间的变异性 (0.90对0.93) 和4.6毫米的 Hausdorff 距离中位数相当的 Dice 得分.
- 在AF患者中,心率变化没有显著影响轮质量.
- 基于CNN的流量量化显示出与半人工方法的良好一致 (r > 0.90),平均速度,静止和净流量偏差最小.
结论:
- 开发的CNN使得在AF患者的RTPCMRI中实现可行和准确的自动化LA流量量化.
- 人工智能方法可以节省大量的时间,而不会影响轮或流量测量的质量.
- CNN对心跳变化的适应性使其成为AF管理中临床应用的强大工具.
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