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Updated: May 9, 2025

Profiling Individual Human Embryonic Stem Cells by Quantitative RT-PCR
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Profiling Individual Human Embryonic Stem Cells by Quantitative RT-PCR

Published on: May 29, 2014

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基于scRNA-Seq的转录组分析和相关的生物信息学方法揭示了研究人类精子生成的新见解

Xiaolong Wu1, Hanchao Liu2, Lin Hua2

  • 1Department of Urology and Andrology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. wuxiaolong@zju.edu.cn.

Advances in experimental medicine and biology
|April 29, 2025
PubMed
概括

单细胞RNA测序显示,塞尔托利细胞对男性生育能力至关重要. 这些细胞的干扰会导致非阻断性亚精子症等条件的精子生成失败.

关键词:
基因分析 基因分析人类的精子生成 (spermatogenesis)不孕不育 不孕不育 不孕不育一个单细胞RNA-Seqq.

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Sequencing Small Non-coding RNA from Formalin-fixed Tissues and Serum-derived Exosomes from Castration-resistant Prostate Cancer Patients12:13

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相关概念视频

RNA-seq03:21

RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while...
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