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Updated: May 9, 2025

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通过酸化Rpd3/HDAC1,PKA在调节基因表达和代谢适应方面发挥着保留作用

Wenjing Dai1, Qi Yu1, Rui Ma1

  • 1State Key Laboratory of Biocatalysis and Enzyme Engineering, National & Local Joint Engineering Research Center of High-throughput Drug Screening Technology, College of Life Sciences, Hubei University, Wuhan, Hubei, China.

Nature communications
|April 29, 2025
PubMed
概括

蛋白激酶A (PKA) 通过调节SAGA复合体来控制代谢适应. PKA 抑制了 Rpd3L/HDAC1 脱乙酶的活性,促进了细胞代谢转移以利用营养.

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