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Updated: Jul 1, 2026

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细胞外囊泡的工程,以有效的细胞内输送多式疗法,包括基因组编辑器

Xiuming Liang1,2,3,4, Dhanu Gupta5,6,7, Junhua Xie8,9

  • 1Division for Biomolecular and Cellular Medicine, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden. xiuming.liang@ki.se.

Nature communications
|April 29, 2025
PubMed
概括

研究人员设计了细胞外囊泡 (EVs),以有效地在细胞内输送治疗药物. 这种新的平台能够进行强大的基因组编辑,并通过减少全身炎症来证明治疗潜力.

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Methods of Nuclear Reprogramming01:24

Methods of Nuclear Reprogramming

Nuclear reprogramming is a process of transforming one cell type into an unrelated cell type by epigenetic changes that alter the cell’s original gene expression pattern. Such epigenetic changes force cells to express a different set of genes, which play a significant role in inducing transformation into other cell types. Nuclear reprogramming offers applications in reproductive cloning for livestock propagation and regenerative medicine — developing patient-specific cells for injury repair.