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Updated: Jul 9, 2026

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全基因组的CRISPR查确定了LRP1作为SFTSV的入口因素

Chen Xing1,2, Cong Zhang1,3, Zhihao Xu4

  • 1Department of Microbiology, School of Basic Medical Sciences, Anhui Medical University, Hefei, China.

Nature communications
|April 29, 2025
PubMed
概括

严重发烧与血小板缺血综合征 (SFTS) 是一种危险的传播疾病. 研究人员发现,低密度脂蛋白受体相关蛋白1 (LRP1) 对于SFTS病毒进入至关重要,将其确定为潜在的治疗标.

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CRISPR01:59

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Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced Short...
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Bacteria and archaea are susceptible to viral infections just like eukaryotes; therefore, they have developed a unique adaptive immune system to protect themselves. Clustered regularly interspaced short palindromic repeats and CRISPR-associated proteins (CRISPR-Cas) are present in more than 45% of known bacteria and 90% of known archaea.
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Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced Short...