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Updated: May 9, 2025

Generation of Cationic Nanoliposomes for the Efficient Delivery of In Vitro Transcribed Messenger RNA
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使用分裂-Ugi反应合成可离子化脂聚合物,用于肺部输送各种大小的RNA和基因编辑

K Yu Vlasova1, A Kerr2, N D Pennock3

  • 1Department of Pharmaceutical Sciences, College of Pharmacy at Oregon State University, Corvallis, OR, USA.

Nature communications
|April 29, 2025
PubMed
概括

研究人员开发了新的电离性脂聚合物,以有效地传递mRNA. 这些纳米粒子有效地向肺细胞和免疫细胞,显示系统性基因疗法和癌症治疗的前景.

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