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Updated: May 9, 2025

A Knowledge Graph Approach to Elucidate the Role of Organellar Pathways in Disease via Biomedical Reports
07:35

A Knowledge Graph Approach to Elucidate the Role of Organellar Pathways in Disease via Biomedical Reports

Published on: October 13, 2023

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蛋白质相互作用,网络药理学和机器学习共同工作,预测与超性心肌病症中线粒体功能障碍相关的基因

Jia-Lin Chen1,2, Di Xiao1, Yi-Jiang Liu1

  • 1The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, NO.55, Zhenhai Road, Siming District, Xiamen, 361003, Fujian, China.

Scientific reports
|April 29, 2025
PubMed
概括

研究人员确定了CCAAT/增强剂结合蛋白三角形 (CEBPD) 作为高性心肌病 (HCM) 的关键基因标. 在HCM模型中较低的CEBPD水平表明它可能是治疗点,Abt-751显示出作为候选药物的潜力.

关键词:
生物信息学是一种生物信息学.过度缩性心肌病变性是一种心脏病变.免疫微环境是一个微环境.机器学习 机器学习线粒体功能障碍 线粒体功能障碍分子对接是分子对接.

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