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Updated: May 9, 2025

Examination of Proteins Bound to Nascent DNA in Mammalian Cells Using BrdU-ChIP-Slot-Western Technique
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Published on: January 14, 2016

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蛋白脱乙酶HDAC10控制恶性淋巴细胞中的DNA复制

Andreas O Mieland1, Giuseppe Petrosino2, Mario Dejung3

  • 1Institute of Toxicology, Mainz University Medical Center, Mainz, Germany.

Leukemia
|April 29, 2025
PubMed
概括

基斯脱乙酶10 (HDAC10) 通过调节DNA复制,对白血病细胞生存至关重要. 抑制HDAC10会触发癌细胞的亡,同时保护正常细胞,提供一种潜在的新型淋巴细胞恶性瘤治疗方法.

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