在Marchantia polymorpha中对INDETERMINATE DOMAIN (IDD) 基因家族的全面分析为进化发育生物学带来了新的见解
Congye Zhou1, Ting Yang1, Manlei Cai1
1State Key Laboratory of Crop Stress Biology for Arid Areas and College of Life Sciences, Northwest A&F University, Yangling, Shaanxi, 712100, China.
BMC genomics
|April 29, 2025
概括
在Marchantia polymorpha中,INDETERMINATE DOMAIN (IDD) 基因家族在进化过程中得到保存,并与SHORTROOT (SHR) 和SCARECROW (SCR) 蛋白相互作用. 这项研究揭示了早期陆地植物祖先的SHR/SCR-IDD通路的洞察力.
科学领域:
- 植物发育生物学植物发育生物学
- 进化遗传学的进化遗传学
- 分子植物科学 分子植物科学
背景情况:
- 草根 (SHR) 和草 (SCR) 对于植物细胞命运至关重要.
- 该SHR-SCR途径涉及各种植物过程中的未确定域 (IDD) 转录因子.
- 一种早期的陆地植物Marchantia polymorpha拥有七个IDD基因,但它们在这个血统中的作用尚不清楚.
研究的目的:
- 在Marchantia polymorpha.中对IDD基因家族进行分类和表征.
- 调查MPIDDs的进化保护和功能角色.
- 在祖先的陆地植物环境中探索SHR/SCR-IDD路径中的相互作用.
主要方法:
- 对IDD基因家族的遗传学分析.
- 基因结构,蛋白质动机和蛋白质结构预测.
- 调节性元素预测,表达分析,亚细胞定位,自动激活试验和酵母两杂交相互作用研究.
主要成果:
- MpIDDs被分为七个保留的分支,具有类似的核心域组织.
- MpIDDs显示出潜在的激素和应激反应,组织特异性表达和核定位.
- 证实了MpSHR/MpSCR和特定的MpIDD蛋白之间的相互作用,突出显示了SHR/SCR-IDD通路的保存功能.
结论:
- 生物信息和实验分析提供了关于MpIDD基因家族的全面信息.
- 这项研究加深了对进化发育生物学中MpIDD功能的理解.
- 这些发现强调了SHR/SCR-IDD途径在植物发育和进化中的重要性.
相关概念视频
Gene Evolution - Fast or Slow?
7.0K
The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
In contrast, regions which code...
7.0K
Conservation of Protein Domains Over Different Proteins
10.6K
Protein domains are small structurally independent units that are part of a single amino acid chain. Although these domains are often structurally independent, they may rely on synergistic effects to perform their functions as part of a larger protein. Protein domains may be conserved within the same organism, as well as across different organisms.
A limited set of protein domains often duplicate and recombine during evolution. These domains can be organized in different combinations to...
A limited set of protein domains often duplicate and recombine during evolution. These domains can be organized in different combinations to...
10.6K
Evolutionary Relationships through Genome Comparisons
5.6K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
5.6K
Gene Duplication and Divergence
6.0K
The seminal work of Ohno in 1970 popularized the idea of gene duplication and divergence. DNA sequence comparison studies reveal that a large portion of the genes in bacteria, archaebacteria, and eukaryotes was generated by gene duplication and divergence, indicating its critical role in evolution.
The duplicated copies of the gene are called Paralogs. Paralogs with similar sequences and functions form a gene family. Across several species, a large number of gene families are...
The duplicated copies of the gene are called Paralogs. Paralogs with similar sequences and functions form a gene family. Across several species, a large number of gene families are...
6.0K
Determination
16.9K
During embryogenesis, cells become progressively committed to different fates through a two-step process: specification followed by determination. Specification is demonstrated by removing a segment of an early embryo, “neutrally” culturing the tissue in vitro—for example, in a petri dish with simple medium—and then observing the derivatives. If the cultured region gives rise to cell types that it would normally generate in the embryo, this means that it is specified. In...
16.9K
Morphogenesis
23.4K
Plant morphogenesis—the development of a plant’s form and structure—involves several overlapping developmental processes, including growth and cell differentiation. Precursor cells differentiate into specific cell types, which are organized into the tissues and organ systems that make up the functional plant.
23.4K


