2019年新冠肺炎 (COVID-19) 患者和非Omicron患者之间的胸部成像差异:系统性审查和元分析
Yingying Han1, Zhijia Wang2, Xingzhao Li3
1Department of Neurology, China-Japan Union Hospital of Jilin University, Changchun, Jilin Province, China.
BMC infectious diseases
|April 29, 2025
概括
与早期菌株相比,COVID-19的Omicron变种在胸部CT扫描上显示出不同的肺部感染模式. 这些发现有助于诊断和管理未来的SARS-CoV-2变种.
科学领域:
- 放射学 放射学是一门学科.
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
背景情况:
- 新型冠状病毒疾病2019 (COVID-19) 构成了全球健康的重大威胁.
- 了解像Omicron这样的SARS-CoV-2变种的演变对于公共卫生至关重要.
- 胸部计算机断层扫描 (CT) 在评估COVID-19肺部参与方面发挥着至关重要的作用.
研究的目的:
- 用胸部CT来比较Omicron和非OmicronCOVID-19菌株之间的肺部感染差异.
- 分析感染Omicron与非Omicron菌株的CT阳性COVID-19患者的胸部CT特征.
主要方法:
- 发表文章的系统审查和元分析.
- 搜索了主要的科学数据库,包括PubMed,Embase,Web of Science和CNKI.
- 使用 Stata 14.0 软件进行随机效应模型的元分析.
主要成果:
- 包括8126名患者,4113名患者患有Omicron,4013名患者患有非Omicron菌株.
- 欧米克朗变异患者CT阳性 (OR=0.14) 的可能性较低.
- 在CT阳性病例中,Omicron患者表现出非典型的肺部特征 (OR=4.02),中心和单叶病变 (OR=4.51,OR=1.72),较少的双边肺部参与 (OR=0.33),较多的支气管壁加厚 (OR=1.99),以及较少的疯狂铺路模式 (OR=0.51),线性不透明度 (OR=0.26) 和血管扩大 (OR=0.54).
结论:
- 胸部CT上的Omicron和非OmicronCOVID-19菌株之间存在病变分布和表现的显著差异.
- 这些发现支持SARS-CoV-2正在进行的演变.
- 结果为诊断和治疗未来变种提供了宝贵的见解,并为公共卫生战略提供了信息.
相关概念视频
Imaging Studies for Cardiovascular System III: X-Ray
106
The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
106
Radiological Investigation I: X-ray and CT
170
Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...
170
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
2.4K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Medical History
2.4K
Imaging Studies for Cardiovascular System II:Types of Echocardiography
200
Echocardiography plays a role in assessing cardiac health and detecting heart conditions, with various types providing critical insights for diagnosis and treatment.
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for...
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for...
200
Imaging Studies for Cardiovascular System I:Echocardiography
260
Cardiac imaging studies encompass a wide range of noninvasive and minimally invasive techniques designed to visualize the heart's structure and function in detail. One such technique is echocardiography, which uses high-frequency ultrasound waves to produce detailed images of the heart, known as echocardiograms.
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...
260
Radiological Investigation III: Pulmonary Angiogram and PET Scan
73
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
73


