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Updated: Jun 23, 2026

Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia
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建模和模拟,以告知阿皮克萨班在急性淋巴细胞白血病或淋巴细胞淋巴瘤治疗asparaginase的儿科的剂量

Praneeth Jarugula1, Toni Ajavon-Hartmann1, Obinna Obianom2

  • 1Bristol Myers Squibb, Lawrenceville, New Jersey, USA.

Clinical pharmacology and therapeutics
|April 30, 2025
PubMed
概括

阿皮克萨班显示出在患有白血病或淋巴瘤的儿童中预防血栓的潜力. 一个人群的药理动力学模型证实了儿童患者的适当剂量,支持其作为抗血栓治疗的使用.

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