相关实验视频

Updated: Aug 14, 2026

Bilateral Common Carotid Artery Occlusion as an Adequate Preconditioning Stimulus to Induce Early Ischemic Tolerance to Focal Cerebral Ischemia

Bilateral Common Carotid Artery Occlusion as an Adequate Preconditioning Stimulus to Induce Early Ischemic Tolerance to Focal Cerebral Ischemia

Published on: May 9, 2013

内血管再血管化的影响功能连接和认知在症状慢性内 Carotid 动脉封闭患者的功能连接和认知:一项初步探索性研究

Renjie Ji¹, Shixin Zhang², Hanfeng Chen¹

¹Department of Neurology, The First Affiliated Hospital, School of Medicine, Zhejiang University, 310003 Hangzhou, Zhejiang, China.

Journal of integrative neuroscience

|April 30, 2025

概括

症状性慢性内动脉封闭 (CICAO) 的功能连接 (FC) 障碍与认知能力下降相关. 内血管再通道可能改善FC和认知,基线DMNFC预测恢复.

科学领域:

神经科学是一个神经科学.
神经学神经学
放射学放射学是一门学科.

背景情况:

症状性慢性内动脉闭塞 (CICAO) 与中风和认知衰退有关.
内血管再通道治疗用于降低中风风险,但其认知效应需要进一步调查.
这项研究探讨了功能连接 (FC) 变化及其在CICAO患者在重血管化前后的认知影响.

研究的目的:

在症状慢性内动脉封闭 (CICAO) 的患者中调查大脑功能连接 (FC) 的改变.
检查这些FC变化与认知功能之间的关联.
评估内血管再血管化的对CICAO患者FC和认知的影响.

主要方法:

招募了18名CICAO患者和15名健康对照 (HC).
使用休息状态功能磁共振成像 (rs-fMRI) 和神经心理评估.
在患者组内血管回血化前和6个月后收集的数据.

主要成果:

与HC相比,CICAO患者在背部注意网络 (DAN),默认模式网络 (DMN),视觉网络 (VN) 和前端对象网络 (FPN) 中显示了减少的FC.
降低的DAN FC与认知得分 (MMSE,MoCA,BDST) 有正相关,与TMT-A和TMT-B有负相关.
内血管再通道导致DMN和VN的FC增加;手术前的DMNFC与TMT-A改善积极相关.

结论:

FC 干扰可能会导致症状性 CICAO 的认知衰退.
内血管再血管化显示出改善这些患者的FC和认知功能的潜力.
基线DMN FC可能预测术后认知恢复,特别是对于执行功能措施,如TMT-A.

关键词:

阴道动脉,内部的阴道动脉.认知功能障碍认知功能障碍功能性磁共振成像技术功能性磁共振成像技术神经心理测试神经心理测试血管阻塞血管阻塞

更多相关视频

A Rat Model of Middle Cerebral Artery Occlusion/Reperfusion Without Damaging the Anatomical Structure of Cerebral Vessels

A Rat Model of Middle Cerebral Artery Occlusion/Reperfusion Without Damaging the Anatomical Structure of Cerebral Vessels

Published on: May 17, 2024

Author Spotlight: A Novel Approach to Cerebral Ischemia Modeling – Enhancing Reperfusion and Simplifying Procedure

Author Spotlight: A Novel Approach to Cerebral Ischemia Modeling – Enhancing Reperfusion and Simplifying Procedure

Published on: May 31, 2024

相关概念视频

Arteries of the Head and Neck

Arteries of the Head and Neck

The human body's intricate network of arteries ensures that every organ system receives the necessary oxygen and nutrients for optimal function. The arterial network in the head and neck region is particularly complex, providing vital blood flow to the brain, eyes, and other critical structures. Prominent arteries in this region include the internal carotid arteries and the vertebral arteries.
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...