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早期的纵向发育在一个多样化的前景队列中,有 Sagittal, Unicoronal 或 Metopic Craniosynostosis
Alexis L Johns1,2, J Gordon McComb3,4, Mark M Urata1,5
1Division of Plastic and Maxillofacial Surgery, Children's Hospital Los Angeles, Los Angeles, CA, USA.
概括
患有骨突症 (CS) 的儿童表现出平均早期发育,但延迟是常见的,特别是在metopic CS. 持续的查对于语言和运动技能的发展支持至关重要.
科学领域:
- 儿科手术 儿科手术
- 发育儿科 发育儿科
- 头骨面部异常 头骨面部异常
背景情况:
- 非综合性关节缩症 (CS) 涉及部部的过早融合,可能会影响神经发育.
- 早期的外科干预是标准的,但纵向发育结果需要进一步阐明.
研究的目的:
- 纵向评估非综合征性CS.儿童早期发育的情况.
- 将发展与规范数据进行比较,并根据手术时间和社会人口统计因素分析结果.
主要方法:
- 对268名CS儿童进行开放式,单阶段手术的前性纵向队列研究.
- 使用贝利婴幼儿发展尺度第三版 (Bayley-III) 预手术和手术后6,18和36个月评估的发育.
主要成果:
- 平均贝利-III分数始终处于临床平均范围,与测试规范相似.
- 发育迟缓 (<第10百分位) 在27%的美托皮病例,20%的斜病例和15%的独角兽CS病例中被观察到.
- 较高的分数与女性性别,更高的社会经济地位,私人保险和美国出生的父亲相关.
结论:
- 虽然平均发育是平均的,但显著比例的CS儿童经历了延迟,特别是在语言和总体运动技能方面.
- 社会人口统计学因素影响发展,强调了有针对性的查和支持的必要性.
- 发育轨迹普遍稳定,由于队列的早期干预模式,与早期手术时间没有明确的联系.
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