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胸前大动脉化作为冠状动脉疾病的预测因素:系统性审查和元分析

Hussein Nafakhi¹, Alaa Salah Jumaah², Akeel Abed Yasseen²

¹Department of Internal Medicine, Faculty of Medicine, University of Kufa, Kufa, Iraq.

Journal of pathology and translational medicine

|April 30, 2025

概括

胸前动脉化 (TAC) 与冠状动脉疾病 (CAD) 的存在和严重程度密切相关. 下降主动脉和主动脉根中的化与其他主动脉段相比,与CAD的关联性更大.

科学领域:

心脏病学心脏病学
血管生物学血管生物学
医疗成像医学成像

背景情况:

胸前大动脉化 (TAC) 和冠状动脉疾病 (CAD) 之间的关联是复杂的和争论的.
关于胸前大动脉不同段与CAD进展和结果之间的关系,存在相互矛盾的证据.

研究的目的:

调查胸前大动脉化 (TAC) 与冠状动脉疾病 (CAD) 的存在和严重程度之间的相关性.
为了澄清胸前大动脉的特定部分与CAD之间的关系.

主要方法:

1990年1月至2024年9月期间发表的研究的系统审查和元分析.
包括PubMed,Scopus或EMBASE索引的研究,检查了TAC和CAD之间的联系.
利用随机效应模型计算了 TAC 与 CAD 存在和严重性相关的聚合概率比率和置信区间.

主要成果:

包括17项研究,共8187名参与者;2775人患有CAD.
TAC与CAD的存在有显著的相关性 (OR,3.874;95% CI,2.789至5.381).
TAC显示与严重的CAD有更强烈的关联 (OR,8.005;95% CI,2.611到24.542).
下降大动脉 (53.4%) 和大动脉根部 (51%) 的化与CAD有着最强烈的联系.

结论:

胸前动脉化 (TAC) 与冠状动脉疾病 (CAD) 的存在和严重程度显著相关.
与大动脉或上升大动脉相比,下降大动脉和大动脉根中的化与CAD更为密切相关.

关键词:

大动脉的化.冠状动脉疾病是一种冠状动脉疾病.进行元分析分析.胸部大动脉的胸部大动脉

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