全球肉食动物宿主和犬病毒 (CDV) 基因型的地理分布:范围审查和空间元分析
A Wipf1, P Perez-Cutillas2, N Ortega1
1Animal Health Department, Faculty of Veterinary, University of Murcia, Murcia, Spain.
Transboundary and emerging diseases
|April 30, 2025
概括
狗病毒 (CDV) 显示出广泛的宿主适应性,在家养狗和野生食肉动物之间在全球传播. 其多样化的基因型凸显了在相互连接的环境中控制这种多宿主病原体的挑战.
科学领域:
- 兽医病毒学 兽医病毒学
- 野生动物疾病生态学 野生动物疾病生态学
- 分子流行病学分子流行病学
背景情况:
- 新兴病毒性疾病在全球范围内越来越普遍,受到气候变化和人类活动的影响.
- 狗病毒 (CDV) 是一种广泛传播的病原体,影响着家养和野生食肉动物.
- 了解CDV的传播动态对于野生动物和公共卫生至关重要.
研究的目的:
- 系统地审查和分析全球分布和肉食动物宿主中的CDV遗传多样性.
- 为了确定CDV的主要宿主和地理谱系.
- 评估家禽和野生动物种群之间的CDV溢出程度.
主要方法:
- 1985年至2024年间在PubMed和Web of Science发表的研究的系统综述.
- 纳入标准侧重于检测CDV的研究,并在食肉动物宿主中测序其基因型.
- 使用QGIS对160篇选定的论文进行了数据提取,质量评估和空间元分析.
主要成果:
- 在332个测序记录中,在17个主要基因型中检测到CDV,主要是Caniformia (93.7%),特别是Canidae,Mustelidae和Procyonidae.
- 全球最常见的基因型是欧洲/南美-1,欧洲-3/北极,亚洲-1和美国-1.
- 狗 (Canis lupus familiaris) 和红狐 (Vulpes vulpes) 是最常见的宿主,有证据表明多个野生家族中的CDV血统,表明频繁的溢出事件.
结论:
- CDV表现出显著的多宿主适应性和遗传多样性,促进其在各种食肉动物物种中传播.
- 某些CDV血统的广泛分布反映了互联世界的宿主迁移模式.
- 在国内野生界面不断的溢出现象使控制CDV传播的努力复杂化.
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