一个回顾性分析在不列颠哥伦比亚省乳牛中死后的沙门氏菌都柏林病例
Ellen Boyd1,2, John Dick3, Christine Millar1
1Ministry of Agriculture and Food Government of British Columbia Abbotsford BCCanada.
Transboundary and emerging diseases
|April 30, 2025
概括
在不列颠哥伦比亚省,奶牛的沙门氏菌都柏林感染病例正在增加. 农场管理实践似乎是这种牛病原体传播的最重要因素.
科学领域:
- 兽医微生物学 兽医微生物学
- 牛的传染病 牛的传染病
- 流行病学 流行病学
背景情况:
- 沙门氏菌都柏林是一种影响乳牛的重要细菌病原体,在北美报告的发病率和多药耐药菌株正在增加.
- 自2015年以来,在不列颠哥伦比亚省沙门氏菌都柏林病例的增加促使对其传播动态进行了调查.
研究的目的:
- 描述2007年至2021年在不列颠哥伦比亚省动物健康中心 (AHC) 诊断的沙门氏菌都柏林病例.
- 确定与英国哥伦比亚省乳制品农场间沙门氏菌都柏林传播相关的风险因素.
- 评估被动,基于实验室的监测数据中的潜在偏差.
主要方法:
- 关于在AHC诊断的沙门氏菌都柏林病例的历史数据的回顾性分析.
- 统计分析以确定风险因素,包括年龄和农场级变量.
- 评估来自不列颠哥伦比亚省各地乳制品农场的实验室提交模式.
主要成果:
- 观察到在AHC诊断的沙门氏菌都柏林病例的时间增加.
- 牛犊受到影响的可能性明显高于成年牛 (OR=38.43).
- 农场场所解释了大部分 (92%) 无法解释的差异,表明农场层面的管理是关键因素.
结论:
- 农场层面的管理实践可能是不列颠哥伦比亚省奶牛群中沙门氏菌都柏林感染的最关键风险因素.
- 临床症状是可变的,呼吸道症状是常见的,特别是在小牛.
- 未来的研究应该集中于阐明有助于沙门氏菌都柏林传播的特定农场管理实践.
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