关于COVID-19严重程度的警告指标:一项回顾性观察研究,整合了现代生物标志物和传统的舌头特征
Zhang Jing1,2, Liu Yuntao3, Zheng Danwen4
1Department of Pulmonary and Critical Care Medicine, Xiamen Hospital of Traditional Chinese Medicine, Xiamen, Fujian, China.
Frontiers in medicine
|April 30, 2025
概括
通过将传统中医的舌头特征与临床生物标志物相结合,可以预测COVID-19的早期严重程度. 这种整合,包括年龄,发烧和PCT,改善了早期检测,特别是在资源有限的环境中.
科学领域:
- 综合医学是一个整体的医学.
- 在COVID-19研究中,研究人员进行了COVID-19的研究.
- 诊断生物标志物 诊断生物标志物
背景情况:
- 准确早期识别严重的COVID-19对于及时干预至关重要.
- 传统中医 (TCM) 提供了独特的诊断见解,例如舌头的特征.
- 整合不同的诊断方法可能会提高预测准确度.
研究的目的:
- 为了识别COVID-19严重程度的早期预警指标.
- 研究将TCM舌头特征与现代医学生物标志物相结合的实用性.
- 开发一个更准确的模型来预测严重的COVID-19结果.
主要方法:
- 这是一项对409名住院COVID-19患者的回顾性观察研究.
- 根据既定的指导方针,分为严重和非严重的分层.
- 对人口统计,症状,TCM舌头特征和实验室参数 (包括公素) 的分析.
- 应用单变量分析和阶段逻辑回归来进行预测器识别.
主要成果:
- 预测COVID-19严重程度的重要预测因素包括年龄,发烧,高甲素 (PCT),厚的舌头毛皮和脂肪的舌头形状.
- 整合这些因素的综合预测模型显示出高性能 (Nagelkerke R2 = 0.741).
结论:
- 在TCM中,舌头的特征 (厚厚的毛皮,脂肪形状) 是COVID-19严重程度的有价值的早期预警指标.
- 将TCM舌头特征与临床生物标志物 (年龄,发烧,PCT) 的整合显著提高了早期识别严重的COVID-19的可能性.
- 这种综合方法在资源有限的环境中特别有益,以改善患者管理.
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